Treatment of Other Causes of Delayed Puberty (4)	

Girls starting with 10µg of ethinyl-oestradiol per day may have their dose increased to 20µg and up to 30µg per day for the first twenty-one days of the month over several years. After breakthrough bleeding occurs, medroxyprogesterone acetate is added in a dose of 10mg per day, given on days twelve through twenty-one of the month. In this way, a normal menstrual period is simulated by the administration of exogenous hormones.